Автор: Steven G.Elliott, Mary Ann Foote, Graham Molineux
Издательство: Birkhauser Verlag
Год издания: 2009
isbn: 3764386940
Количество страниц: 337
Язык: english
Формат: PDF
Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the erythropoietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as a recombinant protein, much was written about EPO. Although much has been learned and published, new, exciting data are becoming available on almost a daily basis. Erythropoietins and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology compiles both pertinent historical and very recent research on this molecule and its clinical utility. The book is divided into two sections: Background and Basic Science and Clinical Uses of Recombinant Erythropoietins. To begin, Israels and Israels describe the biology of red cells, the hierarchy of erythropoietic progenitor cells, their development to mature cells, and the effects of endogenous EPO on their development. Foote summarizes the historical interest in, and search for, an erythropoietic factor. Once EPO was identified, cloned, and expressed, the path was set for the study of other aspects of EPO biology both within erythropoiesis and other cellular systems.
Автор: Gerard Henrotin
Издательство: H&L Publishing
Год издания: 2003
Количество страниц: 68
Язык: english
Формат: PDF (scan)
Content: Early developments of "Machinepistols"; Early Browning type pistols with selective fire; The STAR Machinepistole Model 1922; Mechanical features of the Colt 1911-A1; Joe Ramos' first machinepistole prototype; Joe Ramos' second machinepistole prototype; Operation of the J.Ramos' selective fire system; Front folding grips and other improvements; Final step: The Combat Submachine Pistol.
Издательство: Правда
Год издания: 1974
Количество страниц: 15
Язык: русский
Формат: DJVU
"Журнал ""Крокодил"" - главный юмористический журнал СССР. В каждом номере - актуальные и злободневные юмористические и сатирические произведения, фельетоны и много смешных карикатур. Первый номер журнала увидел свет 27 августа 1922 года. Сначала это был еженедельник, а с 1932 года «Крокодил» стал выходить 3 раза в месяц. В 1972 году журнал награжден орденом Трудового Красного Знамени. В середине 1980-х годов тираж «Крокодила» составлял немыслимые по сегодняшним временам 5 млн. 600 тыс. экз. В 1970-80 годы в журнале публиковались фельетоны В.Канаева, Р.Киреева, А.Моралевича, С.Бодрова, Ю.Борина, А.Ходанова, А.Вихрева; юмористические рассказы С.Комиссаренко, Б.Привалова, Л.Наумова, Б.Ласкина, М.Казовского, Е.Шатько и др. Замечательные карикатуры рисовали Г.Огородников, Г.Андрианов, Ю.Черепанов, С.Спасский, Е.Ведерников, В.Добровольский, Е.Гуров, И.Сычев, В.Мочалов. Проводились разнообразные конкурсы среди читателей."
Автор: Jeffrey S.Levinton
Издательство: Cambridge University Press
Год издания: 2001
isbn: 0521803179
Количество страниц: 634
Язык: english
Формат: PDF
Evolutionary biology enjoys the peculiar dual status of being that subject which clearly unites all biological endeavors, while occasionally seeming to be nearly as remote from complete understanding as when Darwin brought it within the realm of materialistic science. Somehow, the basic precepts first proposed by Darwin have never been either fully accepted or disposed, to be followed by a movement toward further progress in some other direction. The arguments of today – the questions of natural selection and adaptation, saltation versus gradualism, and questions of relatedness among organisms – are not all that different from those discussed 100 years ago, even if the research materials seem that much more sophisticated.