Post-Genomic Perspectives in Modeling and Control of Breathing (Advances in Experimental Medicine and Biology)
	Категория: Медицина, здравоохранение, Генетика, иммунология, бактериология, Биологические науки
		Автор: Jean Champagnat, Monique Denavit-Saubie, Gilles Fortin, Arthur S. Foutz, Muriel Thoby-Brisson Издательство: Springer Год издания: 2004 isbn: 0306485079 Количество страниц: 342 Язык: english Формат: PDF Размер: 17 Мб Каталожный номер: 38510	This publication is placed within the general framework of post-genomic neurobiology, pathology, and the precise example of the rhythmic respiratory neural assembly being used to understand how genetic networks have been selected and conserved in the vertebrate brain. Specific topics include ion channels and synapses responsible for respiratory rhythmogenesis and plasticity; pre- and post-natal development of the respiratory rhythm; chemosensory transduction and chemo-afferent signalling. These valuable insights open new avenues as to why the genetic codes underlying a vital function such as breathing have been selected, conserved, or optimized during evolution - a major issue of post-genomic biology. This critical issue will be considered from both top-down and bottom-up integrative modeling standpoints, with a view to elucidating the functional genomics linking discrete molecules to the integrated system that regulates breathing Ключевые теги: Genomic
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